??? Full Loom vs Mix ???

I don’t have a ton of experience in cables so take it with a grain of salt.

But I feel mix is better for the most part. I believe each company, certain cables perform better than others. A company that makes fantastic power cables don’t necessarily make fantastic speaker cables or RCA or USB.

But here’s something significant to think about, your amplifier might synergize really well with power cable from X company, but your speakers might not perform well with the speaker cable from the same company.

So TLDR, I think loom can be quite tricky.

A mix has worked well for me I've gotten close to a full loom a few times and always backed off. My Jorma/Kondo/Auditorium23/Audio Note UK mashup works really well together. However it is all about finding synergy.

In over 25 years, I've never used a full loom of cables in any of my audio systems.  Currently, I'm using 3 different brands of cables in my audio system with excellent results.     

Mix for sure a few good reasons stated above.

I used a full loom and it was too much of a good thing.  I now go mixed.

Because aural memory is short, and fraught with personal bias issues, unless you can make cable comparisons in your own system, over a reasonably long period of time, you are mostly just pissing in the wind. Of course, cable manufacturers are going to tell you that you are missing out on the “magic” unless you have a “full loom” of their cables.  IME, that is just marketing baloney.  Try different configurations of known, well-constructed cables and use what sounds good to you in your system.  You can read a lot on these forums but IME, 10% of system cost is a good “ballpark” goal.  Go much higher, and a component upgrade will probably be a better value.  Also, for the best value, try and buy used. Once they leave the store, cables are worth about 50-60% of their original cost.

I use a full loom of WyWires Platinum Juice II Series Power cords and a mixture of signal csbles.