Buzz from mouse in speaker

You might be expecting too much from an audio interface that costs the same as a takeout dinner for two made with parts that costs the manufacturer the price of a jumbo fries. Try substituting with something better and send it back if it doesn’t help. Trying an audiophile DAC meant for playback (instead of an inexpensive audio interface from a music store) in your system, for example, costs nothing if you only use it to troubleshoot the problem. Or borrow one from a friend.

If it doesn’t fix the problem you can delve deeper into computer optimization (switching USB ports, disabling onboard audio on MB, changing mice (try wired, not wireless if you haven’t yet, USB isolator as mentioned above etc. etc) which is beyond the short answers that you will see here.

Try using a USB isolator (like a Topping HS01) between your computer and the M-Track Duo.

I don't think it's your mouse. I connected my mouse to the usb port on my streamer and heard no difference. 😉

@czarivey 

Thank you for your replys. Getting rid of the computer is sadly not an option, as i use it for music production and recording. 

Ihave tried moving the soundcard and amplifier as far off as possible, with no change. 

It is indeed an asus motherboard. However, i´m reluctant to replace it after replaceing the PSU to no avail. What makes me question is that i actually get rid of the interference when i connect my external soundcard to the active speaker instead of the amp. Any sugestions on how to troubleshoot this before investing in a new mobo?

Last time I remember having an issue remotely like this it was actually related to the video cables/screen.  Try moving those away from your speakers, replacing the video cable, etc.

sorry i didn't realize that to kill the buzz from mouse in the speaker, you need to set up a mouse trap.

Next time say it this way, “Buzz in speaker from mouse.”

I didn’t want to read your post at first because I thought you had a live mouse in your speaker making noise.  Ewwww.

Anyway, what they all said.  The computer is a noisy source.  Ditch the computer and hire a band- or build/buy a dedicated music server.

Hey, I just realized why speaker ports are so high off of the floor- so mice can’t get in.

Has it evaded you?  Computer sound is noisy.

Enjoy.

I use Lenovo Q190 2012 model. It was made actually as a streamer, because it's DEAD quiet and has SSD to make it even more quiet. 

Recently installed W10, because W7 not in support anymore.

@dundeyr 

My best guess is that the source of the problem is coil whine from the motherboard. i have tried replacing the PSU to no effect. 

I think you're right.

Some Asus motherboards do exhibit this kind of behaviour, and no doubt other makes must do too.

I can however not hear it in a pair of headphones.

My Asus PC does the opposite.

It's clean through speakers but has that faint ghostly interference through headphones.

It´s also transfered if i connect from the onboard motherboard audio card straight to the amp.

Have you tried using a dedicated soundcard?

This is something I intend to try once I can figure out how to install it into the PC.

So many different cards, so many different motherboard sockets ...

Computers are noisy. Get all computers as far away from sound reproduction gear as you can.

Ditch the computer and use a streamer.  The problem with computers is....noise.