It will depend on who you ask, but most people who believe in investing in quality cables including me will say yes. I say it like this because any cable thread is bound to go south on this forum.
Sub cables typically have differences in both the conductor and/or dielectric (shielding) to prioritize the current delivery of lower frequencies and needed speed without worrying about the tone of the higher frequencies. Grounding quality is also highly paid attention to as many sub cable runs are longer and use RCA, whereas typical RCA interconnects should be 2M or less as to keep noise at a minimum.