I see lot's of recommendations of what you "should" do, such as
- pull out the speakers from the wall
- add a bunch of acoustic treatment and bass traps
These are all "perfect world" recommendations and tend to be "knee-jerk" responses without really paying attention to what the OP's situation really is.
I have been in large open weird rooms similar to what bigfatpaulie has. I will say that acoustic treatments can actually make things worse sometimes and need to be done one step at a time. Sometimes, a particular bass trap or acoustic panel can ruin the sound (yes, I have experience with this). I had a room almost exactly like his and put acoustic panels on the front wall between the speakers - and it completely ruined the sound; made it anemic and totally weak. So, if you are doing acoustic treatments, do one at a time and listen carefully.
Second thing is the speaker placement. Because you are having to put the speakers very close to the wall, I would highly recommend looking for speakers that are either sealed box or have a FRONT vent port for the bass. Speakers with a rear vent will not work very well when placed that close to the wall.
Now on to the speakers you mentioned. Wilson speakers are generally very revealing and very fast responding. They tend to have a bright harsh edge with some equipment because they are so fast and require special consideration when you choose preamp/amp/cables. I have heard Wilsons sound excellent with McIntosh and some tube amps, but they definitely sound harsh/bright and fatiguing with some of the higher resolution equipment. Be mindful of this if you are looking at Wilson. The Sophia 1 have aluminum woofers and titanium dome tweeter, which are definitely going to sound bright. The newer generations typically use Scanspeak drivers, which are also bright and fast responding.
I have always loved Sonus Faber speakers. They are very natual sounding and also very neutral sounding. They sound great with many different amps/preamps and they are more forgiving to bad electronics/cables. Excellent choice. However, the tweeters are soft-dome which are nice but do not have as much resolution/transparency in the very high frequencies. This means they are not as detailed or revealing as other speakers with different tweeters. They are still not a bad choice.
The Focal speakers are also completely different. They are extremely clean sounding. But in my opinion, they are so clean sounding that they lack texture and "grit" for all the different tones and resonances. They can also sound thin in the midrange with a lot of systems. You really have to hear the speaker to decide if you like this type of sound.
Another speaker that you could potentially look at are the Revel PerformaBe series. They are very high resolution but without the harsh edge of wilson and have good bass with a front port. At this point, we will probably have another 5-10 different speaker recommendations because everybody thinks their speakers are the "best". I always try to describe how a speaker sounds instead of trying to tell you what speaker I think you should get, lol.