Putting them on their side, even if the tweeters are still at ear level, with pretty drastically damage their sound reproduction.
The drivers, enclosure, and crossovers are all designed for the speakers to be vertical, width of the enclosure, the distance of the acoustic centers of the different drivers, the vertical and horizontal off axis response, etc.
Laying them on their side will affect all of the above.
I can guarantee imaging and soundstage, one of the things that those speakers do exceptionally well, will be pretty much nonexistent.
Moving your head, even slightly, up or down, left to right, will very noticeably alter frequency response.