I'm not sure if my positioning is unique or not but I'll describe it:
I'm set up in my living room. My couch and love seat are in an 'L' configuration and the couch is the focal point.
An end table sits between the couch and the love seat. I have the sub under the end table and it points away from the listening area making it a source for background and filling in. There's a caveat however.
For the sub to sound its best and to 'disappear', you have to be at the focal point of my listening area. I have the speakers tilted a slight amount. If you leave the listening area, then the sub no longer disappears. As a matter of fact, its presence is very evident.
I mentioned the sub points away from the listening area so behind the love seat, you have a birds eye view of the sub's grill and it is very noisy back there. The only one that does not seem to mind is my dog lol