I think it depends on where you are and your timeframe. If your system is all brand new in a new location… that is one thing, if you have an existing system… something else.
I do a system upgrade every 5 - 10 years. I change speakers typically every 10 - 15 years. So, I start with components. I would never start with interconnects or cables… this stuff is highly component / system dependent. I upgrade to the very best and compatible components and listen a lot. Get to know the sound of my upgraded system. Definitely take your time. Nuances mater.
You have a great power conditioner. I can’t remember if you put in direct lines. These always help… so, whenever you get around to it.
Then, if speakers are new… speaker cables (these can be huge if you have significantly changed your system.. Then power cord for amp. Then interconnects, then the rest of the power cords. At this point your system should be performing really well and time for detailed room treatments.
I would never do components last… it can negate all the work you just did.