Ah, the the resurgence of the Post Modern World Vision. My goodness, I hope not... "The bounds of science can not contain the human mind" (Toynbee).
Well hifiman5, your hero was also credited with the quote, Civilizations die from suicide, not by murder. Seems to me that embracing a false reality, especially with how the physical world actually works, is far more threatening to social development.
So, back to the subject at hand: Do speaker cables need a burn in period? Answer: Only if you believe the advertising written by Cardis, AudioQuest, SilTech, WireWorld and a few others. I think Albert Einstein must have been in the midst of just this sort of conundrum when he complained to a Princeton, NJ newspaper reporter, "Two things are infinite: the universe and human stupidity; and I'm not sure about the universe."