Fuses make a difference, Donavabdear said no fuse is better than a fuse. I wonder about that. I have bypassed fuses and have been shocked by how much better my system sounded. Fuller bass, expanded sound stage to name a couple, but I wonder if the Synergistic fuses don't also perhaps bring some subtle filtering into the system all the while somehow increasing current flow.
If you can't hear a difference in either wires nor fuses, you are truly blessed. The money you will save will be significant! Ignorance is bliss!