Will increasing speaker cable AWG make a difference in sound quality?

@thespeakerdude, 

Does tend to get a little claustrophobic in here at times, can you blame any of us :-) 

This is an area that cable geometry can make a difference.  I would suggest listening to several cables and go with what sounds best.  

You have to remember that not only speakers but to a lesser extent cables exhibit impedance, and together they form a impedance circuit. 

 To lessen that effect use thicker/lower gauge wire.

From Roger Russell (former McIntosh Director of Acoustic Research)

Wire Table

This is hard to beat.

Wire Gauge: 16 AWG
Capacitance: 35pF/m
Inductance: 0.52 µH/m