I’ve heard the 2170 with the Spatial Audio M3 Sapphires and the Magnepan LRS… both with and without the Audio Kinesis 4 sub array… and with and without room correction.
I found it to always sound good, never bright or harsh, good imaging and soundstage… as for room correction and mating to the subs… no issues…but the 2170 has other built in sound corrections one might actually prefer.
With the 2170 the Spatials had tons of dynamics and punch…. The LRS displayed a beautiful midrange. Overall, I think the 2170 could work well with many speakers.
I also heard the 2170 being used as a preamp driving the Halo A21…compared to the Lyngdorf amp, the sound produced by the Halo was better in every respect for the two speakers above…. but not by a big margin.