First and foremost, what is your budget?
What kind of music do you listen to?
What kind of sound quality characteristics do you seek?
What kind of sound quality characteristics do you want to avoid?
How big is your room?
How loud do you play?
I've had a Ref 75SE for 2 weeks--great amp! It's got drive and is well balanced so I think it could work with a lot of different speakers. Depends what you're going for. I am currently using it with Totem Tribe Towers in a somewhat compact space. Like the ARC amp, the speakers are detailed but even keeled. Fed by an MSB Analog DAC, I'm quite happy.