First, if you find something you like the sound of, stick with it!
The all-in-one machines provide convenience above all else, but there’s a big difference in the user interface, that is, the software as well as possibly the sound quality. They could be better sounding, or could be worse. Truth is the Oppo’s had great sounding DACs and while some combination units may be better, they may also not be.
Personally, I’d say that the big reason to look for a change from where you are is usability and fewer pieces of gear in your rack.