The best audio tweak is a soft bristled paint brush...

For those fragile lacquer and wood finishes microfibre cloths are a safe choice. 

I keep a couple of natural bristle brushes in my toolbox for such purposes.

Once every few years I'll give my amplifier circuit board a good dusting with a gentle brush.

My PC on the other hand, seems to need it once or twice a year.

In particular, the CPU fan/heatsink.

Oh, I should mention, I do not use a water dampened washcloth on paper/pulp speaker drivers. Just on the speaker cabinet and on poly driver cones as well as electronic component exteriors. 

It occurred to me that a barber's soap brush is a soft and gentle for such dusting. Even the platter of my TT benefits. 

Here's another great one: A water dampened washcloth to wipe down speakers and components. Followed by a soft, dry cotton towel.

For 40 years I've never used any chemical product to clean an audio component.

Every house painter that I have seen carries an old brush to use as a "duster"  I too have used one for years to dust off every piece of equipment. Great to get between tubes in your amp or in crevices in the TT, or just the platter. Yes indeed, a paint brush is right there under my TT ready for dusting.

Steve Deckert recommends them for dusting his amps. 2-inch, soft natural bristles. I took his advice. Works great.