Target bias dictated by amp or by tube?


If my amp's (Line Magnetic 508ia) manual says to adjust bias of each power tube to 120ma on the front meters, but a set of after market replacement tubes (Cossor Valve 508) state their bias should be set to 65ma, which stat should I be following when putting in the new tube?
divertiti
@brotw The voltage should be dictated by the amp as only the amp designer knows what the real plate voltage is. Go 120ma my friend 
@divertiti , I've been listening to the Cossors on my LM508 for a couple of weeks now, biased at the LM suggested 120ma. Naturally this post grabbed my attention.Have you seen an advertised bias current for the Cossors? The testing data sheets for all 4 tubes say measured - 60ma at the specified plate voltages. Spec or QA test results for matching pairs?
You might try splitting the difference, during your tests(ie: around 90 - 100mA). If you don’t notice an audible reduction in presentation(lost dynamics, rounded off highs, poor focus, etc), compared to the manual’s spec, leave it there. Why waste tube life?
If one were to use the lower of the two, which means it would be running out of spec according to the amp, does the amp simply produce less power or will the sonic qualities suffer as well?
The power will be unaffected.
The sound quality will likely be inferior at the lower bias. Bias plays a huge role in an amp's sonic character. Try both but I bet you'll prefer the higher setting. 
Appreciate the answer. If one were to use the lower of the two, which means it would be running out of spec according to the amp, does the amp simply produce less power or will the sonic qualities suffer as well?
The lower one, if you want your tubes to last. The higher one, if you want the amp to perform to design spec.

Tube bias is an ever-shifting target. In the majority of amps where bias is fixed the designer/manufacturer has been forced to choose a bias that will deliver whatever power and tube life they are going for. The tradeoff is higher power/lower tube life. The main tradeoff, not the only one. Amps like Prima Luna can get around this with active bias, but this is not easily (read, expensively) implemented.