So I would think that generally speaking, if one had an amp with only 8 ohm taps (which is probably includes quite a few amps) one shouldn’t even consider speakers with 4 ohms listed as nominal impedance.
I’ll let the more knowledgeable and experienced answer most of what your questions are, but regarding this, the manufacturer would know the answer to what the capability of his amp is.
With the Coincident Frankenstein stereo 300B, I noticed it had 8 ohm taps only, so I asked the designer/owner if a 4 ohm speaker is fine, and the answer was that the 8 ohm taps are fine for any speaker from 4 to 12 ohms.
And this is what the manufacturer of my 45 amp states, but he is Japanese so read through the translation:
"An 8-ohm terminal has come out of 1 set of speaker terminal of this machine.
However, the speaker from 4ohms to 16ohms can be used.
Since it will lead to a sound quality fall if a middle terminal is prepared in an output transformer, it is being dared to make the output terminal into 1 set.
Although a little maximum output falls by speakers other than 8 ohms, a sound has little change and it can be satisfactorily used for it."
I can confirm both amps sound fantastic with my 4 ohm speakers; no idea if the tubes will last longer because of the "reduced maximum output" or if other factors are in place. I have heard my speakers are a flat and "easy" 4 ohm load, but I can't confirm.