With a familiar cartridge on my own rig, 30-45 minutes is typical for a reasonable setup. After that I tweak while listening... a never-ending process, as Onhwy61 noted.
That's after 10 years of working with multiple tonearms and dozens of cartridges. It used to take days and several gallons of sweat, lol.
I use just three tools: a small screwdriver, an alignment protractor and a VTF scale. Like many, I've got all kinds of gizmos but I now find they add little if any value to the process or the result.