Depends. You are correct that the user interface UI does not impact sound quality anymore than my TV's remote control affects movie quality, but Roon is a different matter.
Roon is a 3 layer (read: over-engineered) system with a UI, a core which handles all library and DSP functions and end points. In the case of Roon, the core touches all audio streams, there’s no way to avoid it. It does offer some neat features like a wide range of sample rate conversion (PCM to DSD, up/downsampling, MQA unfolding, etc.) as well as per device EQ.
As a result, the Roon UI has no sound but the Roon playback system might.