Relieving the tube amps and the midbass drivers of the bottom octave or so should reduce distortion on both. Those large frequencies hog a lot of power from the amps and cause large excursions to the midbass drivers. If you can find out your amps input impedance, you could try a couple of inline filters (I used 10nF silver mica caps at a cost of < $20)
80hz-ish is a good option for two reasons...it keeps the sub playing in the range where it isn't directional, and it leaves just about the entire vocal range to the midbass driver.
If you don't already have a sub, you might consider using two subs to help break up room nodes. Most subs already have a built in low and high pass crossover, which could make it really simple to try.