Will the quality of the PC make an appreciable difference for me?
A more powerful computer won't improve sound quality, but it will allow computer to "get out of tthe way." so to speak.
that means
- no computer fan noise (silent PC or laptop)
- a custom power plan which allows the mainboard to perform without much power consumption
- fast storage (like solid-state drives / NVMe, fast RAM, and a decent CPU for accessing large (or any) audio files quickly on playback software
Always get a good USB cable or a custom one to avoid issues with audio latency/packet errors or ghosting.