Audiophile system with Yamaha core and wired main and wireless remotes

What would be your recommendation for an audiophile system with a Yamaha receiver or integrated Yamaha amp being the center piece (defining the sound), feeding a pair of wired towers and sub (mains) and two pairs of wireless remote speakers (simultaneously) in a large open loft space, sourcing TT, CD, Tape, tuner and streaming services. 

I’m currently gobbling together a solution involving an R-2000, an RCA switch, a phono pre, a Wiim Pro+ and two Wiim Minis, two towers and a sub for the mains and four smaller powered speakers for the remotes/rears. 

But I’m suspicious that there is a better, more simple, more user friendly way to achieve this, without sacrificing the signature higher-end Yamaha sound quality. Less footprint, less gadgets, less wires would be a plus. 

How would you go about this. I’m interested to hear your thoughts for both approaches: building it from scratch or with some of the devices I already own (as in above). 

Thank you!