I have mine on low (3 available speeds) and can't hear them. Things seem to stay cool enough. Might need a higher speed if your room is hot, but them you wouldn't want the amp on for super long anyway.
Biasing is pretty easy. I think the VT100 is known to be one or the worst ARC amp to bias.
It's a pretty great amp. I considered replacing it with a REF160S, but they are quite heavy (close to 100 lbs?) and I suspected the 160S will be replaced or augmented with a new amp that uses the KT170 tubes. I think I am correct about this, as the 320M became the new 330M with KT170 tubes.