I used an LS2 with Classe CA-300 for several years so I can relate somewhat to your situation. I tried several cap upgrades on my LS2 which mostly brought it up to MkII status, i.e. replacing a number of RelCaps with MIT caps. Your preamp already has the MITs which are a pretty good sounding cap IMO. I have no doubt, however, that V-Caps would sound better based on my testing V-Caps in several components (but not the ARC). There are a couple issues though. First, if you are using the LS2B in balanced mode, you have 4 output coupling caps to replace. As I recall, the output caps were a 5uf MIT (with a .01uf MIT bypass) for the single-ended outputs and either a 1.0 or 2.0uf MIT for the balanced output (also with a .01uf MIT bypass). You do NOT need to use the same values for replacement caps. The Classe amp has a pretty high input impedance so a 5uf is total overkill. If I were you, I would replace the 5uf caps with a single 1.0uf V-Cap per channel and no bypass cap. If you are using the preamp single-ended, you do not need to replace the output caps on the balanced outputs. If you are using it balanced, then replace the 1.0 or 2.0uf caps with again a single 1.0uf V-Cap without a bypass cap.
There are other caps in the LS2 circuit that affect the sound quality such as the bypass caps in the power supply, but you will get the most bang for the buck with the output coupling caps. Therefore, I would do them first and get a good feel for how they sound before tackling any other parts. It is possible to have too many V-Caps.
Here's another factor to consider: The ARC circuit boards are double-sided and each cap lead is soldered on both sides. This makes for a very reliable connection but also makes it difficult for the average solderslinger to replace parts. It can be done but it's not as easy as you might expect.
Dave