I'd prefer monos; however it depends on how the equipment is designed.
I have used to own Moon's M400 mono blocks and they are excellent. The 330A is a heck of an amp and I chose the M400 versus having to buy 2 Y adapter XLRs.
I currently own the Moon 860A V2 and it has a switch on the back to run as a mono. If I saw another black Moon 860A V2 at a great price I'd consider picking it up :) and running them as mono blocks.