Speaker for McIntosh setup

Redwood, 
I have a new pair of Heresy's with my Mac 240 and I am completely enthralled. For me the set up just sounds like a perfect fit. I added an SVS PB 2000 and that really rounded everything out. This is the sound I've been chasing for so long now. Mostly listen to jazz and rock of all kinds. I used to sell TDL transmission lines and owned three pair over the years. Great neutral sounding speaker, harder to drive, fickle with amplification and set up. But these Klipsch Heresy's have really opened up my listening experience. I know there are a couple camps when it comes to horn loaded drivers and I was a hold out for a very long time. I picked mine up from Audio Classics in NY. They were great to work with and since I had about a 6 hour drive to get to them, Audio Classics had several set up for my listening session. If you are anywhere near them do yourself a favor and make an appointment with Ryan. 

I have found that really good components can get the most out of decent speakers. But of course to get the most out of your system requires complimentary quality speakers. I have run some $3K speakers on $30K of electronics for years. The speakers were ribbon so they really did perform over there cost... but ultimately I wasn’t betting the most out of my system.

"Note: The system is in a large great room."

My advice would be to make sure you get speakers that are large enough. I have heard great speakers sound not good because they were in rooms too large for them. You lose bass and without the low end it sounds off. This was in a double story great room. You may end up needing a sub so consider that in the budget.

I run Focal with my McIntosh and love it.

I've been happy with Sonus faber speakers - and at $5k the Sonneto V is right in your price range.

McIntosh is better paired with neutral/fast sounding rather than warm/slow speakers. So, B&W, Dynaudio, Focal, Raidho, etc will be generally good matches.