Yes, but i have a tester.... it's risky with 4 pin antique tubes and also any rectifiers though . Most of my tube gear has modern equivalent or type is still made. I do have a bunch of e180f and 5r4gy/ 274b on hand so no worries.
Would you buy a tube amp if you were unable to use vintage tubes in it ?
Not available or too expensive.
Hmm.., I don't think I have a definitive answer for myself, but I would do my best to avoid such amps. There is no substitute for great tubes, I guess, especially if you value sophisticated sound.