I wouldn’t buy anything new that relied on vintage products to sound good. Kinda silly really but there is something for everyone.
Would you buy a tube amp if you were unable to use vintage tubes in it ?
Not available or too expensive.
Hmm.., I don't think I have a definitive answer for myself, but I would do my best to avoid such amps. There is no substitute for great tubes, I guess, especially if you value sophisticated sound.