Running in parallel would result from sending the + output to the + in speaker 1 and the + in speaker 2. The - output would also be sent to both the - in speaker 1 and the - in speaker 2. This could either result from a) running two wires from the + output to the + of each speaker and two wires from the - output to the - of each speaker or b) running one wire from the + to speaker 1 and then running another wire from the + in speaker 1 to the + in speaker 2 (ditto on the -).
Running in series would result from sending the + out to the + in speaker 1. Run another wire from the - in speaker 1 to the + in speaker 2. Run another wire from the - in speaker 2 to the - output.
Running in parallel cuts the impedence in half so it might sound louder in the rear and the amp has to be able to handle and impedence that low (e.g., an 8 ohm impedence turns into a 4 ohm impedence overall). Running in series doubles the impedence so it might sound quieter in the rear but the amp should have no issues.
Running in series would result from sending the + out to the + in speaker 1. Run another wire from the - in speaker 1 to the + in speaker 2. Run another wire from the - in speaker 2 to the - output.
Running in parallel cuts the impedence in half so it might sound louder in the rear and the amp has to be able to handle and impedence that low (e.g., an 8 ohm impedence turns into a 4 ohm impedence overall). Running in series doubles the impedence so it might sound quieter in the rear but the amp should have no issues.