Here is the checklist that I run through in my mind whenever I install a cartridge, of things that need to be adjusted or at least considered:
Overhang.
Offset angle.
Azimuth.
VTA.
Tracking force.
Anti-skating force.
Load resistance (i.e., preamp input impedance).
Load capacitance.
It seems to me that any of the first six items on this list could account for the symptoms you are hearing, if not properly set.
Regards,
-- Al