One of the most overlooked considerations, from my chair, is the amp to driver interfacing, starting with getting rid of the passive crossover between the amp and speaker/its drivers. That naturally necessitates doing the crossover duties prior to amplification on signal level (i.e.: active configuration) and having a dedicated amp channel for each driver section, which in turn means amp load independency between each of these sections. This way (i.e.: both getting rid of the passive crossover on the output side of the amp and having each amp channel drive a limited frequency span) the individual amp channels will see a significantly easier load presented to them, thereby making more effective use of their power envelope and quality potential; finally control the drivers better with direct driver connection and harnessing more of their potential as well.
Next is higher speaker efficiency, or ideally no less than ~95dB sensitivity across the board to lessen thermally induced compression issues (not least as a dynamic phenomena with dulled transient response), and to aid overall ease and fluidity of reproduction. (Then there's the importance of matching directivity patterns, especially at crossovers between different driver sections for good, smooth power response).
When combining above two (or three) aspects in speaker design, a significant bottleneck in audio reproduction has been addressed. Active configuration isn't just about removing the passive crossover as the perhaps most "visible" measure, but as well - by the same token - to make way for amp load independency in each of their sections, which in turn affects driver performance and accuracy.