No. :) You also can’t.
I mean, there’s an upper limit to what the DAC will accept, so you can’t do 8x and 8x upsampling for instance.
Try both and use the one that sounds best. With older DACs upsampling made a much bigger difference than it does now.
There is a possibility in diffferences in upsampling technology. How exactly they each calculate the intermediate samples varies.
With modern DACs it seems that the biggest difference I hear has to do with the roll off filters and how upsampling affects that frequency response. With older DACs (10 years or older) upsampling would make a huge difference, and hi rez files were a big improvement over Redbook CD playback