agree with trial and error. i added some jm reynaud cantabile speakers to my system and found some big differences in sound with how i wired them. this was the first bi-wire speakers i've had, and had no idea on the best way to set these up. first round was using a single wire cable from the amp to the high frequency connections on the speaker with the factory jumpers to the low frequency terminals. the sound was extremely bright and fatiquing. after 2 days, i switched the single wire cable to the low freq terminals with the jumpers in place for the high freq terminals. this was much better- more bass, very enjoyable sound. due to the differences i discovered, i decided to bi-wire them and found even more improvement. more clear, with a more balanced sound.