I will 3rd the Epos.
I have heard the 5350se with the M12 (i think that's what they were called - the Epos bookshelf speaker) and it was a really good combo. Crisp, clean, detailed. Perhaps a bit 'hot' for my liking. I would imagine that with cabling, this could be tuned to your liking.
Make sure you switch the stock jumpers for something a bit better. And I would use full-bodied sounding speaker cable if you go with this combo.
I have heard the 5350se with the M12 (i think that's what they were called - the Epos bookshelf speaker) and it was a really good combo. Crisp, clean, detailed. Perhaps a bit 'hot' for my liking. I would imagine that with cabling, this could be tuned to your liking.
Make sure you switch the stock jumpers for something a bit better. And I would use full-bodied sounding speaker cable if you go with this combo.