The issue with single driver speakers is covering the entire freq spectrum humans are capable of hearing. I've owned Omega and Jordan single drivers, both were unsatisfactory in this regard. I suppose one could add subs and super tweeters, but I'd expect major problems with integrating them, and you've lost the principle of simplicity.
Single way or multiway
The founder and builder of the highly respected high-end speaker company Gauder Akustik, Dr. Gauder, says that using a full-range driver is very bad. He uses 3- to 4-way speakers with extremely complex 10th-order crossovers consisting of 58–60 components.
In contrast, some other well-known and equally respected speaker companies — such as Voxativ, Zu, Cube Audio, and Totem — use crossoverless designs.
Who is right, and who is wrong?