A major consideration where run of the mill measurements completely miss the mark is the materials used in the drivers themselves. For example, Kevlar, polyprop, etc used in drivers that measure perfectly...you might as well throw a blanket on your speaker before you started listening.
This is one of the reasons i don’t like the low effort/resources brands who buy mass market drivers from someone else and put it in a box. It takes some guy who has put serious thought into the materials used in drivers and developed his own from scratch.
We could go on about crossovers, etc... barrel bottom quality components in crossovers can still measure perfectly. With sim software, you can very quickly design great crossovers, But, as you move up in quality of components used, the sound totally changes, i.e. the measurements say little about "quality" (whatever that word means to you).
Last, but not the least, humans perceive way too much in transients (spatial nuance, etc). The configuration (Drivers+crossovers+box) that gets botched w.r.t the latter, no matter how great it measures with traditional measurements will sound like a ..."meh".
The above mentioned perhaps falls into the "esoterica" (dismissed) category for the ASR type of guy, another reason i despise that loathsome forum.
