Finally, what would your experience with the 45 SET amp suggest as far as the optimal efficiency rating for these tiny two watts?As with all things audio, it depends. It depends on your ears, your expectations, your gear (listed), the size, shape and construction of your room, how loudly (or softly) you typically play music and, mostly, your ears.
I ran a pair of Omega Super Alnico 6 monitors as my main speakers for a couple of years, paired most often w/ both a 2W 45 SET mono blocks or a 5W SE EL34 amp. I loved them and thought they were great for most non-headbanging music but weren't quite cutting it with large orchestral and opera pieces. Maybe it was the single driver or maybe it was the whizzer cone. I ended up replacing them with something completely different that isn't low-powered tube friendly. That's not to say I don't miss the Omegas - I do.
But to answer your question, 2W is enough when it's enough. And it's not when it's not. If you like the sound of the Omegas but you can't play loud enough, get an amp that puts out more horsepower. I had a McIntosh MC225 (25 W PP) and it really changed how the Omegas sounded. Not better or worse, just very different. If you don't like the sound of the Omegas then changing amps probably won't make you happy. My motto is speakers first: find a speaker you love and will work with your music and your room and then find the right amp to optimize the speaker. Others here may have a different opinion.