Roon+Multiple Zones with 2 Dacs.

Have an idea I was going to try. Wanted to run 2 dacs in my system. One feeding my amp and speakers, and one feeding 4 subwoofers. I would use roon and combine zones to have the same music play out of both dacs at the same time. Am I going to have timing issues? I wanted to use minidsp in between the DAC and subs. A couple reasons for this. Biggest one would be integrating each subwoofer to cover a certain frequency response, different from each subwoofer.  Second one would be to have room correction for the subs and not for the speakers. I would love to have room correction for bass while not correcting anything to my speakers themselves. IE: front 2 subs close to Speakers for mid bass only, other 2 subs used for lower frequencies only. Or maybe add 2 more subs and use 4 for low frequencies and 2 for midbass, or vice versa. Any thoughts? Anyone tried anything similar?