inpep, of course what has to be done within a component is to convert the ac into dc which the component then reconverts into ac in the form of the music. There may be some components that use the 60 Hz frequency, such a cheap turntables. In such circumstances 50 Hz would matter.
The reason why fuse direction matters is obscure. Some claim that it is determined by the direction the various wires getting from the wall to the internal ac must pass. Omega Mikro goes to great extremes with both red and blue ac cables to assure this. There are probably other explanations as well. But in reality it is what you hear that matters. Try reversing one fuse and see if you don't hear a difference and have a preference. If you don't, so be it.
I guess I could also suggest that you try 50 Hz and 60 Hz and see if it makes a difference, but that would be awkward to do. Most manufactures, maybe all manufactures, list their equipment as working on both 50 Hz and 60 Hz ac, but I doubt if they have ever tried it both ways, because they believe, or want to believe, it makes no difference.