Really depends, but often included in the manual. Focal likes little to no toe-in.
Also, some find B&W sounds much better on midrange axis than tweeter axis. Meaning, you want to sit lower, or angle the speaker up.
As a speaker maker Troels Gravesen once commented, and I agree, even when we try to design our speakers to be listened to on tweeter axis sometimes the design just doesn't work out and your best listening position is somewhere in between the tweeter and the midrange.