Don’t mistake iTunes with Apple lossless. The latter is a very good streaming service—on par with Tidal on my system at half the price. But to the question…
In case your system sounds like mine… I A/B tested Apple lossless vs Qobuz for 2 hours last night. I played the same songs on my Audition playlist on both streaming services. 1) Was there a difference? 95% of the time, yes. 2) What were the differences? Qobuz was clearer (very apparent in the bass) and provided a much deeper, expansive, 3-dimensional sound stage. For about the same price, Qobuz was the clear winner. My system is iPad > RME adi 2 > pass labs 250.8 > B & W 803 d3 + 2 Rel s/510s
HTH.