@walt8489
I second all of those that suggest utilizing a quality Roon endpoint as opposed to streaming directly from your Mac Mini functioning as Server/Streamer.
In my case Roon Core is a Roon Nucleus and principal endpoint is a Rose RS130 feeding a Rockna Wavelight via Tubulus Concentus I2S. For Rockna Wavelight, by design I2S all things being equal is the best input.
However, you have a Holo May, and as I understand it, the Holo May folks consider USB to be the best input (good friend has Holo May, and this is what Holo Audio folks told him). So I suggest looking for quality endpoint that features USB output together with a quality USB cable.