I've been considering this one myself. I had a C48, but didn't like it, thought about the C46, but don't like the eq high-end centered on 4k instead of 10k like the older units. I'm currently using a C15, which I keep coming back to, but sometimes it seems a bit shrill on some music.
So what do you specifically like about the C45, and do you use it for 2 channel only, or do you use it in 6 channel for home theater only? Do you have the TM-1 tuner module installed, and if so, is it any good?
I'm also using a MC7200 amp with ADS 1590/2 speakers.