Leave it on?

@mylogic Thanks for bringing up the environmental point. One things folks might do if they want to deal with energy costs to the planet is consider voluntary renewable choice programs, such as the ones offered by companies like Xcel Energy. Consumers can support renewable energy generation, thereby reducing their individual carbon footprint associated with electricity consumption without necessarily putting in solar panels, etc.

Invalid,

Your personal experience represents a small sample size.  Also, it sounds like you experience a lot of tube death in order to detect a pattern.  Is it possible that your gear is hard on tubes, particularly at turn on?  If your gear has tube rectification, turn on of the rest of your tubes will be inherently gentle.  Some tube gear have “soft start” circuits that slowly ramp up the juice.  
Almost all of my gear uses tube rectification.  I’ve been running the same amp and linestage and phonostage for 15 years and I have not replaced any tubes.  I cannot draw any conclusions from personal experience with that kind of data.

We use a Yamaha receiver for our TV sound and just leave it on all the time. It has been on for several years now with no issues. FWIW.

@baylinor 

Turning off every piece of equipment that has an on and off feature in front of the unit and always leaving on the ones that only have a on and off function on the back of the unit. 

What if your amps don’t even have an on/off switch, just an IEC?!  I just leave them powered up all the time.  SMc Audio now uses thermal-magnetic switches (think Swiss Digital Fuse Box) that serves the purposes of both equipment protection (i.e., fuse) and on/off switch.  After sourcing two of them from SMc, I mounted them in-line, in the wall, one for each amp and replaced the line fuses in both amps with copper rod.  At least I can now turn the amps on/off without unplugging them.

For the past 10 years or so, I have been content to have all solid state equipment that I can leave powered up all the time.  It has been a change for me to now have a DAC with tubes that I need to remember to power down.  Even though it seems to take less than an hour to sound its best, my sporadic listening schedule (I often don’t know when or if I will have time to listen each day) makes it more difficult to have equipment that requires some forethought and warm up. 

I do unplug everything when thunderstorms are eminent (seems too often lately) and when I am going to be away from home more than a day or two.  I also occasionally power down my digital chain (server/streamer/DAC) as suggested by @grannyring and seconded by @mikelavigne but I was previously unaware of the Roon clear cache button, so I will also try that. 

No on and off switch anywhere, the designer obviously meant for the unit to be powered on 24/7.