It is a major issue because that breaker is the amplifier/speaker protection. If the breaker trips with the speakers connected and stays on with the speaker cables disconnected, it is probably a short in the speaker and not an amplifier issue. If it trips without the speakers connected then it's an amplifier issue (i.e., DC at the output, internal short or part of the protection circuitry damaged).
It's going to need service to find the cause. A local repair guy may not be able to help without a schematic.