No. Only unclocked USB signals need to be clocked. With modern clocks reclocking is unnecessary.Well, that appears true on the surface. And most people don't specify enough configuration data to rally know. But let me be very clear: with systems running with the source as slave and the DAC as master (clocking), and with stuff that was considered well-clocked when it was new, adding a USB interface with isolation and re clocking has made a huge difference several times.
Note that my data point is NOT a box in the middle, which brings its own can of worms, but a replacement of the coaxial SPDIF provided originally with a custom PCB with independently powered (line powered) USB; full ground, signal and power isolation; clean power to the processing stage, and tight clocking beginning with a read buffer --> then spit out to the DAC. Yes I'm being a little vague.
So while your point is well taken it comes down to "how well is the internal clocking/timing implemented?", "how dependent is it on source timing?" and "how good is the magic box being added".
I tend to agree that i would NOT just add a magic box.