Hi,
I took a look at your system from your profile and I'm thinking before you do anything pull those speakers out a bit from the wall and you'll notice immediately a change in the spacial imaging soundstage etc aspects. Ie. It should sound better.
Cables are highly dependent on a system. Better systems appreciate better cables. Yes all cables sound differently to the extent your system can distinguish them.
I'm not a big fan of the blue sound Device as the dac is not the greatest, but it can be bypassed so that's good