One of my systems uses Wilson Maxx 2s which weigh over 400 lbs. each. The speaker bases are threaded for spikes, but the threading also takes heavy duty commercial casters which helped set up a lot - and while you could (somehow) jack them straight up and swap to spikes, I decided to just lock the casters in place and I doubt whether spiking would improve sound anyway.
FWIW, these speakers are set up with vernier adjustment of the rake angle of the top module (tweeter and two mids) and we set them up using a laser range finder with me sitting in the listening seat, and I have had zero urge to move them (although I did apply markers with carpet tape in case I ever did want to mess about with them.