First welcome to the game. It will never stop, so be careful what you wish for:)
@ghdprentice gave you good advice.
This is a good time to take this real slow. Give a lot of thought to how to do this.
It is very difficult to get high end audio sound from an AVR / home theater. By combining functions both can be severely compromised. The best is to have them completely separated.
I started almost exactly where you did (minus the divorce) but with a Yamaha RXA3080 which was at the time their top of the line AVR. I thought it was pretty good. (I have owned several Denon's prior)
I wanted more so I bought a $3K Line Magnetic Tube amp and was completely blown away (so was my wife). I've moved on since then (new everything on the 2 channel side), but I still use the Yamaha for 5.1. The front speakers are shared - 2 sets of speaker cables. I prefer this inconvenience to having the Yamaha anywhere in the 2 channel chain.
As for subs, for sure get 2. I have 2 RELs that are seamlessly shared between the Raven and the Yamaha.