The Hilo has 6 independent DAC channels only if you are using USB or thunderbolt as input. However, that seems the case in your system. (The SPDIF and AES inputs use a single digital receiver.)
The volume knob can control any of the outputs, but I don't know that there is a way to gang it to control all at once. And it doesn't offer analog-domain control on the line (highest quality) outputs, but it does offer digital-domain control.
I have a Hilo and love it. I am using it in a computer based desktop system with JRiver Media Center and powered speakers. In my system, I found it very easy to implement a crossover in JRMC and drive the (single) sub with the Hilo's monitor outputs. (Just as easy with two subs.) The mains are driven with the line outputs. I use the knob to set relative level of the sub by changing the monitor volume. I use JRMC to set system volume.
I have not heard the exasound.
HTH
Mike