Directionality of wire

Further, Audioquest, a strong advocate of wire directionality, is hardly a one man operation.

I apologize for sounding rude, but please read carefully before you pipe-off. I specifically contrasted AQ as a "big boy" operation.
As to the rest, I don't mind your perspective a bit even though it is not my own. I am hardly an objectivist. I spout the old chestnut, "Not all things that can be measured count and not all things that count can be measured" more often than most people sneeze. I too bought into directionality of all IC's and cables. As I said, Chris Sommovigo made me less certain. 
As to fuses, does the name Roger Modjeski ring a bell? Please (carefully) read this; http://www.audiocircle.com/index.php?topic=105425.0

As I've posted elsewhere, it IS true that I am new to the A-Gon fora. That's because I used to be a regular on AA and it sufficed. But that asylum has become dead and this one seems more active so I've migrated here. I have 40 years experience in the hobby. Sorry for torturing you with big yawns. I know that feeling and my apology is sincere. I am fairly certain that Chris does not ground his IC's on one end and yes, I made an exception for that when I posted. Here are Chris' comments;
https://linkprotect.cudasvc.com/url?a=https://blackcatcable.com/blogs/news/5965201-directionality&c=E,1,CZTsGYkSx3yJ1ygMD6zVhmyvrpZ2uv2n-LeadEheXdsxsgPmIjEiN_cPBDgsM4uiyM9MgcSeSGWoY4E5WadYmr2-97nMZth-m_2kPw,,&typo=1

When it comes to cables, I am open to the majority of concepts that can't be explained or measured by electrical engineers. I DO find it difficult to ignore the advice/philosophy of the maker of the cable on hand. Until recently I was using Chris Sommovigo's Airwave single ended cables between my tubed preamp (Audioprism Mantissa) and tube amp (ARC VS110). I liked the sound I was getting without any experimentation of cable orientation. The sound was not as etched/precise as through my Homegrown Audio Silver Laces but not specifically lacking in any regard. Now, Chris just shipped me a pair of balanced Airwaves to go with my new ARC Ref 6 and ARC Ref 150se. Maybe this time I will experiment. What is one to do with unmarked cables, there are 4 possible combinations of orientation if my rudimentary math skills are correct and I don't know that four combinations can be remembered well from an auditory-brain standpoint. Not knowing when my custom made (one man operation!!!) cables would arrive from Japan, I bought an $80 pair of Mogami Gold Studio XLR's too. I bet they will sound fine. Guess what-no directionality is labeled. Oh no, that means the recording studios are F'ing up too! OK, that was weak-recording studios DO F up the recordings we nonetheless shell out our hard earned money for and suffer. 

How will you do that? You can’t flip balanced cables end to end. All you can hope is the manufacture assembled the ends with the wire direction the same for each balanced cable.

Doh! This dumbass goof on my part demonstrates my lack of experience with balanced cables despite my 40 years in the hobby. Well, I guess I am relieved. Less audio-nervosa! I can just go with the flow. Get it? "Go with the flow". Ha, I kill me.

I'm new here. I posted my OP with sincere interest. I have been informed the topic has been beaten to death previously. I did NOT intend to fan the flames of past bad blood between longstanding participants. I obviously don't get to play referee or league commissioner. The choice is yours. I am just asking.

Ok, back to your corners guys... Let's say wire has a direction created from the formation of the wire, and in theory will pass the signal better one direction vs. the other. But wait... music signal is all AC, so whichever way you place the wire it's still going to be incorrect 1/2 the time, and correct the other half. It's kind of like a tug-o-war where each side pulls the center ribbon back and forth 20-20,000 times per second. It's a lot of work, but unless one side is declared the winner, it makes no difference which way you hook up the wire.

Bingo-exactly what Chris Sommovigo is saying, I believe.Exactly why even with shield to ground schemes, Chris' take made me re-think the entire concept of directionality. If the fish scale on wire surfaces theory espoused by AQ and others were correct, we are left to pre-suppose that any competent producer of balanced cables checks the grain structure before assembling the connectors. I doubt that very much. I don't doubt that there may be a subtle difference with RCA's when you switch them. Very subtle. Sticking one harmonic dot on the ceiling kind of subtle. It could be due to any number of other things than extruding/grain structure such as dialectric anomalies (inconsistent contact or thickness or properties on a microscopic level), solder joints/connections, or other. 

The reason why AC cables AND fuses in AC circuits are directional is because we only hear the effects of the portion of the alternating current that is traveling TOWARD the component.

With all due respect, repeating this falsehood over and over does not make it more true. Every link in the chain of an audio system right down to the cabling involves circuits. As someone else tried to point out to you, your loudspeakers are transducers that rely on both sides of the circuit to, uh, transduce. This is why many of us have phase switching built into our preamps-so that we can correct out of phase recordings. Push-pull applies to more than just amplifiers. It is the underlying foundation of domestic electricity. 

Now, it doesn’t take a rocket scientist which I happen to be

In addition to being a skeptic as to wire directionality, call me a skeptic on this doozy little gem. Please, give us proof! If you prove me wrong I will humbly apologize to you. 

Mr. Kait, as I know you know, there are many threads on multiple boards about you and questioning all aspects of your background, educational, vocational, and otherwise. I am a lawyer. On Monday I am going to send a letter on my letterhead to the University of Virginia to check on your Linkdn claim of an aerospace degree from that institution and I will publish the results here. Best to you sir. For now.